Document Details

Document Type : Article In Journal 
Document Title :
Potential Anticancer Natural Product against Human Lung Cancer Cells
المحتملة المضادة للسرطان المنتج الطبيعية ضد سرطان خلايا الرئة البشرية
 
Subject : Potential Anticancer Natural Product against Human Lung Cancer Cells 
Document Language : English 
Abstract : PM 701 has potential anticancer activity and it caused selective programmed cell death in lung cancer cells (A549) as described previously, this further study is aimed to present the cytotoxic effect of the lyophilized PM 701,and its fraction. Lyophilized PM 701 appears to have cytotoxic activity due to its in vitro inhibition of the proliferation of lung cancer cells. The bio-guided extraction of PM 701 gives fraction PMF (150 mg g-1 of lyophilized PM 701). PMF was able to inhibit significantly the proliferation of A549 cells without affecting the normal, HFS cells. Chromatographic fractionation of PMF produced seven compounds, where the subfraction PMEK (108.7 mg g-1 of PMF) was the most effective one with high anti-proliferative activity against A549 cells. However, the subfraction PMFK is under extensive work in order to isolate the pure bio-active compound (s) in nano-scale levels as a novel pharmaceutical composition 
ISSN : 1319-0989 
Journal Name : Arts and Humanities Journal 
Volume : 4 
Issue Number : 1 
Publishing Year : 1429 AH
2009 AD 
Article Type : Article 
Added Date : Saturday, March 5, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
فاتن خورشيدKhorshid, fathen Researcher  

Files

File NameTypeDescription
 29243.pdf pdf 

Back To Researches Page