Main Page
Faculty Deanship
Dean
Health Empowerment Unit
Strategic Planning Unit
Development and Quality Unit
Medical and Bioethics Unit
Vice Dean for Graduate Studies and Research
Vice Dean for Female Section
Vice dean for Academic Affairs
Examination and Assessment Unit
Internship and Alumni Unit
Student Research Unit
E-learning Unit
Student Mentoring and Support Unit
Community Service Unit
Talent and Creativity Care Unit
Continuing Education Unit
Neuroscience Research Unit
Vice Deanship of Clinical Affairs / Administration
Organizational Structure
Departments
Basic Sciences
Department of Anatomy
Department of Pharmacology
Department of Pathology
Department of Microbiology and Medical Parasitolog
Deparment of Clinical Biochemistry
Department of Physiology
Department of Medical Genetics
Clinical Sciences
Department of Otorhinolaryngology
Department of Obstetrics and Gynecology
Department of Hematology
Department of Medical Education
Department of Anesthesia
Department of Family Medicine
Department of Community Medicine
Department of Surgery
Department of Orthopedic Surgery
Department of ophthalmology
Department of Radiology
Department of Internal Medicine
Department of Pediatrics
Department of Emergency Medicine
Department of Urology
Department of Dermatology
Latest News
عربي
English
About
Admission
Academic
Research and Innovations
University Life
E-Services
Search
Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
“Alterations in the ultrastructure of the liver in chronic lead intoxication in the adult albino rat”
“Alterations in the ultrastructure of the liver in chronic lead intoxication in the adult albino rat”
Document Language
:
English
Abstract
:
In the present work, the effect of chronic lead intoxication in two doses (5mg/kg body weight, as therapeutic dose and 10mg/kg body weight as sublethal dose) on the ultrastructure of the rat liver was studied. The rats were classified into three groups: one control group (10 rats), experimental group A (20 rats) who received a therapeutic dose of lead acetate orally for six months, and experimental group B (20 rats) who received a sublethal dose of lead acetate orally for six months. Ten rats of both groups A & B were sacrificed one month after the last given dose (recovery rats). Small slices of the liver of the rats of all groups were processed for electron microscopic examination. The livers of group A rats showed a few pathological changes in the form of proliferation of both rough and smooth endoplasmic reticulum, multiple areas of glycogen depletion with a few lysosomes and fat droplets. Group B rats showed marked pathological changes in both hepatocytes and Van Kuppfer’s cells. The cytoplasm of the hepatocytes showed intracytoplasmic vacuoles and a few degenerative granules. The recovery animals of group A showed good recovery, while those of group B showed only partial recovery.
ISSN
:
1658-3175
Journal Name
:
Al-Azhar Medical Journal
Volume
:
2
Issue Number
:
38
Publishing Year
:
2009 AH
2009 AD
Article Type
:
Article
Added Date
:
Sunday, March 28, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
شريف حسن
Hassan, Sherif
Researcher
Doctorate
Files
File Name
Type
Description
26227.1
1
Back To Researches Page