Document Details

Document Type : Article In Journal 
Document Title :
Novel methods for the synthesis of some pyridazino-, furo-, and polysubstituted pyridazines
Novel methods for the synthesis of some pyridazino-, furo-, and polysubstituted pyridazines
 
Document Language : Arabic 
Abstract : 3,4-Diethoxycarbonyl-5,6-diphenylpyridazine 1 reacted with hydrazine hydrate to form tetrahydropyridazino [4,5-c]pyridazine 2, which reacted with ethyl bromoacetate to give 6,7-diethoxycarbonylmethyl-3,4-diphenyl-5,8-dioxopyridazino[4,5-c]pyridazine 3. However, acetylation of 2 with acetyl chloride gave three different pyridazino[4,5-c]pyridazines 4-6. The reaction of the starting diester 1 with different amounts of phenylmagnesium bromide gave different products 7-10. The structure of product 8 was elucidated by alkaline hydrolysis and hydrazinolysis to afford 11 and 13, respectively. Treatment of 13 with benzaldehyde in piperidine yielded the starting Grignard product 8 and benzalazine 17. 
Journal Name : SYNTHETIC COMMUNICATIONS 
Volume : 32 
Issue Number : 7 
Publishing Year : 2002 AH  
Added Date : Monday, June 23, 2008 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سوزان محمد بترجيBatterjee S Researcher  
.Shams NAResearcher  
.El-Shahawi MMResearcher  
.Shalaby AAResearcher  

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